Background Anti-C1q autoantibodies can disrupt normal complement function, contributing to the formation of pathogenic immune ...

This article is part of “Innovations In: RSV,” an editorially independent special report that was produced with financial support from MSD, Sanofi and AstraZeneca. Scientists have made monumental ...

This article is part of “Innovations In: RSV,” an editorially independent special report that was produced with financial support from MSD, Sanofi and AstraZeneca. When Laura Ehrlich gave birth to her ...

Fc engineering has many important uses in antibody drug development. It enhances antibody-dependent cellular cytotoxicity (ADCC) in the tumor microenvironment to increase tumor cell-killing efficacy ...

Please provide your email address to receive an email when new articles are posted on . Production of Dengvaxia, the only dengue vaccine approved in the U.S., has been discontinued. Another shot is ...

Ten years ago, the Zika virus shook Brazil. Thousands of babies were born with severe birth defects. Pregnant women faced constant fear, and public health systems scrambled for answers. While the ...

ADCs integrate monoclonal antibodies with cytotoxic payloads, offering new treatment options for NSCLC, including biomarker-selected and biomarker-agnostic patients. ADCs are composed of an antibody, ...

Bispecific antibodies (BsAbs) enhance NSCLC treatment by targeting dual antigens, improving efficacy, and overcoming resistance compared to conventional monoclonal antibodies. Amivantamab and ...

Earlier this month, the Trump administration said it was terminating $500 million in mRNA vaccine research and shifting its focus to other approaches, including a previously announced “whole-virus” ...

(A) Structural propagation pathways originating from galactose residues within the Fc-linked glycan. (B) Galactose residues (indicated by yellow circles) suppress glycan mobility by acting as ...